Mgme1 - mitochondrial genome maintenance exonuclease 1 Gene

Mus musculus

Also known as 8430406I07Rik

Gene ID: 74528 | Gene type: protein coding

About Mgme1

Summary

Predicted to enable single-stranded DNA exodeoxyribonuclease activity. Predicted to be involved in mitochondrial DNA replication and mitochondrial genome maintenance. Predicted to act upstream of or within DNA repair. Located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 11. Orthologous to human MGME1 (mitochondrial genome maintenance exonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Mgme1 Products(4)

mRNA	Protein	Name
NM_001289630.1	NP_001276559.1	mitochondrial genome maintenance exonuclease 1
NM_001289631.1	NP_001276560.1	mitochondrial genome maintenance exonuclease 1
NM_001355688.1	NP_001342617.1	mitochondrial genome maintenance exonuclease 1
NM_028984.5	NP_083260.1	mitochondrial genome maintenance exonuclease 1

Protein Preferred Names

Protein Names

mitochondrial genome maintenance exonuclease 1

mitochondrial genome maintainance exonuclease 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08410	MGME1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20989	Mgme1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27506	Mgme1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mgme1	NCBI	NCBI:92667

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