UGT1A - UDP glucuronosyltransferase family 1 member A complex locus Gene

Homo sapiens

Also known as UGT; GNT1; UGT1; UGT1A@

Gene ID: 7361 | Gene type: other

About UGT1A

Summary

This RefSeq represents a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. [provided by RefSeq, Jul 2008]

Related Diseases

Diseases

Alias

Gilbert Syndrome

Gilbert Disease	Gilbert'S Disease
Gilbert'S Syndrome	Cholemia, Familial
Familial Nonhemolytic Jaundice	Meulengracht Syndrome
Gilbert Syndrome, Susceptibility To	Hyperbilirubinemia, Gilbert Type
Hblrg	Hyperbilirubinemia, Arias Type
Hyperbilirubinemia I	Constitutional Hyperbilirubinemia
Gilbert-Meulengracht Syndrome	Hereditary Nonhemolytic Jaundice
Hyperbilirubinemia Arias Type	Hyperbilirubinemia Type 1
Constitutional Liver Dysfunction	Gilbert-Lereboullet Syndrome
Hyperbilirubinemia 1	Unconjugated Benign Bilirubinemia
GILBS	Gilberts Syndrome
Familial Nonhaemolytic Jaundice	Constitutional Hyperbilirubinaemia
Hereditary Nonhaemolytic Bilirubinaemia	Familial Nonhaemolytic Bilirubinaemia
Idiopathic Hyperbilirubinaemia	Icterus Intermittens Juvenilis
Chronic Intermittent Juvenile Jaundice	Low-Grade Chronic Hyperbilirubinaemia Syndrome
Benign Unconjugated Bilirubinaemia Syndrome	Hereditary Nonhaemolytic Jaundice
Idiopathic Unconjugated Hyperbilirubinaemia	Gilbert--Lereboullet Syndrome
Constitutional Hepatic Dysfunction	Meulengracht Icterus
Cholaemia Familiaris Simplex	Familial Cholaemia
Congenital Familial Cholaemia	Physiologic Cholaemia
Hyperbilirubinaemia Type 1	Gilbert Cholaemia

Bilirubin, Serum Level Of, Quantitative Trait Locus 1

Bilirubin, Serum Level Of, Qtl1	BILIQTL1
Bilirubin, Serum Level Of, Quantitative Trait Locus, Type 1

Hyperbilirubinemia, Transient Familial Neonatal

Lucey-Driscoll Syndrome	Transient Familial Neonatal Hyperbilirubinemia
HBLRTFN	Hyperbilirubinemia, Familial Transient Neonatal
Hyperbilirubinemia Transient Familial Neonatal	Transient Familial Hyperbilirubinemia

Crigler-Najjar Syndrome, Type I

Crigler-Najjar Syndrome	Crigler-Najjar Syndrome Type 1
Bilirubin Udp Glucuronyl Transferase Deficiency	Crigler Najjar Syndrome
Crigler Najjar Syndrome, Type 1	Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency
Bilirubin-Ugt Deficiency	Hyperbilirubinemia, Crigler-Najjar Type I
Hblrcn1	Familial Nonhemolytic Unconjugated Hyperbilirubinemia
Hereditary Unconjugated Hyperbilirubinemia	Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency Type 1
Bilirubin-Ugt Deficiency Type 1	Crigler-Najjar Syndrome 1
CN1	Cn-I
Crigler-Najjar Syndrome Type I	Hereditary Unconjugated Hyperbilirubinaemia
Ugt Deficiency	Bilirubin Glucuronosyltransferase Deficiency
Crigler-Najjar Disease Or Syndrome	Deficiency Of Glucuronosyltransferase
Glucuronyl Transferase Deficiency	Glucuronyltransferase Deficiency
Udp Glucuronyl Transferase Deficiency	Cns - [Crigler-Najjar Syndrome]
Congenital Familial Nonhemolytic Jaundice

Crigler-Najjar Syndrome, Type Ii

Crigler-Najjar Syndrome Type 2	Hyperbilirubinemia, Crigler-Najjar Type Ii
Hblrcn2	Arias Syndrome
Crigler Najjar Syndrome Type 2	Bilirubin Uridinediphosphate Glucuronosyltransferase Deficiency Type 2
Bilirubin-Ugt Deficiency Type 2	Crigler-Najjar Syndrome 2
CN2	Cn-Ii
Crigler-Najjar Syndrome Type Ii	Crigler Najjar Syndrome, Type 2

Bilirubin Metabolic Disorder

Hyperbilirubinemia	Hereditary Hyperbilirubinemia
Hyperbilirubinemia, Hereditary	Hyperbilirubinaemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (19)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-137083	Trifluoperazine N-Glucuronide	Inhibitor	96.6%	Unkown
HY-160250	UGT1A1-IN-1		99.27%	Unkown
HY-137083S	Trifluoperazine N-glucuronide-d3		≥93.0%	Unkown
HY-137083A	Trifluoperazine N-glucuronide chloride		/	Unkown
HY-RS15426	UGT1A1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15427	UGT1A10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15428	UGT1A3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15429	UGT1A4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15430	UGT1A6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15431	UGT1A7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15432	UGT1A8 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS15433	UGT1A9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS16380	UGT1A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS16797	Ugt1a1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19083	Ugt1a8 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21974	Ugt1a4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23238	Ugt1a1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26323	Ugt1a3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27017	Ugt1a Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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