2. Gene
  3. Mutyh - mutY DNA glycosylase Gene

Mutyh - mutY DNA glycosylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Myh; Mutyha; Mutyhb; Mutyhc; Mutyhbeta; Mutyhalpha; 5730495A01Rik

Gene ID: 70603 | Gene type: protein coding

About Mutyh

Summary

Predicted to enable DNA N-glycosylase activity; DNA binding activity; and MutSalpha complex binding activity. Involved in negative regulation of necroptotic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Mutyh Products(3)

mRNA Protein Name
NM_001159581.1 NP_001153053.1 adenine DNA glycosylase isoform a
NM_001316747.1 NP_001303676.1 adenine DNA glycosylase isoform b
NM_133250.2 NP_573513.2 adenine DNA glycosylase isoform a
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of necroptotic process IMP
IMP: Inferred from mutant phenotype
28059467 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenine DNA glycosylase

a/G-specific adenine DNA glycosylase

mMYH

mutY homolog alpha

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08854 MUTYH Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22658 Mutyh Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mutyh NCBI NCBI:4595