2. Gene
  3. Pxdn - peroxidasin Gene

Pxdn - peroxidasin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as VPO1; mKIAA0230; E330004E07; 2310075M15Rik

Gene ID: 69675 | Gene type: protein coding

About Pxdn

Summary

Predicted to enable bromide peroxidase activity and heme binding activity. Predicted to be an extracellular matrix structural constituent. Involved in extracellular matrix organization. Located in collagen-containing extracellular matrix. Is expressed in several structures, including branchial arch; central nervous system; gut; heart; and sensory organ. Human ortholog(s) of this gene implicated in anterior segment dysgenesis 7. Orthologous to human PXDN (peroxidasin). [provided by Alliance of Genome Resources, Apr 2022]

Pxdn Products(1)

mRNA Protein Name
NM_181395.2 NP_852060.2 peroxidasin homolog precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables oxidoreductase activity, acting on peroxide as acceptor IDA
IDA: Inferred from direct assay
22842973 MGI
enables oxidoreductase activity, acting on peroxide as acceptor IMP
IMP: Inferred from mutant phenotype
32571911 MGI
Biological Process GO Annotation Evidence Reference Source
involved in basement membrane assembly IDA
IDA: Inferred from direct assay
22842973 MGI
involved in basement membrane assembly IMP
IMP: Inferred from mutant phenotype
25708780 MGI
involved in basement membrane organization IMP
IMP: Inferred from mutant phenotype
24895407 MGI
involved in cell adhesion IMP
IMP: Inferred from mutant phenotype
24895407 MGI
involved in extracellular matrix organization IDA
IDA: Inferred from direct assay
19590037 MGI
involved in eye development IMP
IMP: Inferred from mutant phenotype
31817535 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
22842973 MGI
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
19590037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxidasin homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11479 PXDN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20331 Pxdn Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26839 Pxdn Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pxdn NCBI NCBI:7837