Aen - apoptosis enhancing nuclease Gene

Mus musculus

Also known as Isg20l1; 2700083B06Rik

Gene ID: 68048 | Gene type: protein coding

About Aen

Summary

Predicted to enable exonuclease activity. Predicted to be involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and response to ionizing radiation. Predicted to act upstream of or within apoptotic process and cellular response to DNA damage stimulus. Predicted to be located in nuclear membrane; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human AEN (Apoptosis enhancing nuclease). [provided by Alliance of Genome Resources, Apr 2022]

Aen Products(3)

mRNA	Protein	Name
NM_001162939.2	NP_001156411.1	apoptosis-enhancing nuclease isoform 2
NM_001360709.1	NP_001347638.1	apoptosis-enhancing nuclease isoform 1
NM_026531.5	NP_080807.3	apoptosis-enhancing nuclease isoform 1

Protein Preferred Names

Protein Names

apoptosis-enhancing nuclease

interferon stimulated exonuclease gene 20-like 1

interferon-stimulated 20 kDa exonuclease-like 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00424	AEN Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19856	Aen Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26356	Aen Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Aen	NCBI	NCBI:64782

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