2. Gene
  3. Atad1 - ATPase family, AAA domain containing 1 Gene

Atad1 - ATPase family, AAA domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Thorase; 4921525H23Rik

Gene ID: 67979 | Gene type: protein coding

About Atad1

Summary

Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in learning or memory; negative regulation of glutamatergic synaptic transmission; and regulation of receptor internalization. Located in postsynaptic membrane. Is active in glutamatergic synapse and postsynapse. Is expressed in central nervous system; ganglia; renal cortex; submandibular gland primordium; and thymus primordium. Human ortholog(s) of this gene implicated in hyperekplexia 4. Orthologous to human ATAD1 (ATPase family AAA domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Atad1 Products(1)

mRNA Protein Name
NM_026487.3 NP_080763.2 outer mitochondrial transmembrane helix translocase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
21496646 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21496646 MGI
Biological Process GO Annotation Evidence Reference Source
involved in learning IMP
IMP: Inferred from mutant phenotype
21496646 MGI
involved in memory IMP
IMP: Inferred from mutant phenotype
21496646 MGI
involved in negative regulation of synaptic transmission, glutamatergic IMP
IMP: Inferred from mutant phenotype
21496646 MGI
involved in positive regulation of receptor internalization IMP
IMP: Inferred from mutant phenotype
21496646 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
21496646 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
21496646 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21496646 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
21496646 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21496646 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
21496646 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
21496646 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
21496646 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

outer mitochondrial transmembrane helix translocase

ATPase family AAA domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10326 Z-ATAD-FMK Inhibitor / Unkown
HY-RS01118 ATAD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21487 Atad1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28005 Atad1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atad1 NCBI NCBI:84896