2. Gene
  3. Kmt5a - lysine methyltransferase 5A Gene

Kmt5a - lysine methyltransferase 5A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Setd8; PR-SET7; PR/SET07; 2410195B05Rik

Gene ID: 67956 | Gene type: protein coding

About Kmt5a

Summary

Predicted to enable histone-lysine N-methyltransferase activity; p53 binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; peptidyl-lysine monomethylation; and regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to act upstream of or within cell division; chromatin organization; and methylation. Predicted to be located in cytosol and nucleoplasm. Is expressed in embryo. Orthologous to human KMT5A (lysine methyltransferase 5A). [provided by Alliance of Genome Resources, Apr 2022]

Kmt5a Products(6)

mRNA Protein Name
NM_001310723.2 NP_001297652.1 N-lysine methyltransferase KMT5A isoform 2
NM_001310725.2 NP_001297654.1 N-lysine methyltransferase KMT5A isoform 3
NM_001310727.2 NP_001297656.1 N-lysine methyltransferase KMT5A isoform 3
NM_001405388.1 NP_001392317.1 N-lysine methyltransferase KMT5A isoform 3
NM_001405390.1 NP_001392319.1 N-lysine methyltransferase KMT5A isoform 4
NM_030241.4 NP_084517.2 N-lysine methyltransferase KMT5A isoform 1.
Protein Preferred Names Protein Names

N-lysine methyltransferase KMT5A

H4-K20-HMTase KMT5A

H4-K20-HMTase SETD8

N-lysine methyltransferase SETD8

PR/SET domain-containing protein 07

SET domain containing (lysine methyltransferase) 8

SET domain-containing protein 8

histone-lysine N-methyltransferase KMT5A

histone-lysine

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12335 UNC0379 Inhibitor 99.90% Unkown
HY-100625 BVT948 Inhibitor ≥99.0% Unkown
HY-12335A UNC0379 TFA Inhibitor 99.91% Unkown
HY-RS07406 KMT5A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18288 Kmt5a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24766 Kmt5a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kmt5a NCBI NCBI:387893