2. Gene
  3. Samsn1 - SAM domain, SH3 domain and nuclear localization signals, 1 Gene

Samsn1 - SAM domain, SH3 domain and nuclear localization signals, 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SLy2; Hacs1; 930571B16Rik; 4930571B16Rik

Gene ID: 67742 | Gene type: protein coding

About Samsn1

Summary

Predicted to enable phosphotyrosine residue binding activity. Involved in negative regulation of B cell activation; negative regulation of adaptive immune response; and negative regulation of peptidyl-tyrosine phosphorylation. Located in cytosol and nucleus. Is expressed in several structures, including cardiovascular system; mesonephros; nervous system; sensory organ; and surface ectoderm. Orthologous to human SAMSN1 (SAM domain, SH3 domain and nuclear localization signals 1). [provided by Alliance of Genome Resources, Apr 2022]

Samsn1 Products(1)

mRNA Protein Name
NM_023380.2 NP_075869.2 SAM domain-containing protein SAMSN-1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of B cell activation IMP
IMP: Inferred from mutant phenotype
19923443 MGI
involved in negative regulation of adaptive immune response IMP
IMP: Inferred from mutant phenotype
19923443 MGI
involved in negative regulation of peptidyl-tyrosine phosphorylation IMP
IMP: Inferred from mutant phenotype
19923443 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
20478393 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20478393 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SAM domain-containing protein SAMSN-1

SAM domain, SH3 domain and nuclear localisation signals, 1

SAM domain, SH3 domain and nuclear localization signals protein 1

SH3 protein expressed in lymphocytes 2

SH3-lymphocyte protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12435 SAMSN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21925 Samsn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28441 Samsn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Samsn1 NCBI NCBI:64092