Nrarp - Notch-regulated ankyrin repeat protein Gene

Mus musculus

Also known as 2700054M22Rik

Gene ID: 67122 | Gene type: protein coding

About Nrarp

Summary

Acts upstream of or within several processes, including angiogenesis; negative regulation of Notch signaling pathway involved in somitogenesis; and somite rostral/caudal axis specification. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; paraxial mesenchyme; and retina. Orthologous to human NRARP (Notch regulated ankyrin repeat protein). [provided by Alliance of Genome Resources, Apr 2022]

Nrarp Products(1)

mRNA	Protein	Name
NM_025980.2	NP_080256.2	notch-regulated ankyrin repeat-containing protein

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of Notch signaling pathway	IMP IMP: Inferred from mutant phenotype	21998026	MGI
acts upstream of T cell differentiation	IDA IDA: Inferred from direct assay	12794108	MGI
acts upstream of or within blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IMP IMP: Inferred from mutant phenotype	19154719	MGI
acts upstream of or within branching involved in blood vessel morphogenesis	IMP IMP: Inferred from mutant phenotype	19154719	MGI
acts upstream of endothelial cell proliferation	IMP IMP: Inferred from mutant phenotype	19154719	MGI
acts upstream of or within negative regulation of Notch signaling pathway	IGI IGI: Inferred from genetic interaction	12794108	MGI
acts upstream of or within negative regulation of Notch signaling pathway	IMP IMP: Inferred from mutant phenotype	21795391	MGI
acts upstream of or within negative regulation of T cell differentiation	IDA IDA: Inferred from direct assay	12794108	MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	12794108	MGI
acts upstream of or within positive regulation of vascular endothelial cell proliferation	IMP IMP: Inferred from mutant phenotype	19154719	MGI
acts upstream of or within regulation of cell-cell adhesion	IMP IMP: Inferred from mutant phenotype	19154719	MGI
acts upstream of or within somite rostral/caudal axis specification	IMP IMP: Inferred from mutant phenotype	21998026	MGI
acts upstream of or within sprouting angiogenesis	IMP IMP: Inferred from mutant phenotype	19154719	MGI
acts upstream of vascular endothelial cell proliferation	IMP IMP: Inferred from mutant phenotype	19154719	MGI
acts upstream of or within vascular endothelial cell proliferation	IMP IMP: Inferred from mutant phenotype	19154719	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

notch-regulated ankyrin repeat-containing protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09557	NRARP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21004	Nrarp Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27521	Nrarp Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nrarp	NCBI	NCBI:441478

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