2. Gene
  3. Sptssb - serine palmitoyltransferase, small subunit B Gene

Sptssb - serine palmitoyltransferase, small subunit B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ADMP; Sssptb; 1110032A04Rik

Gene ID: 66183 | Gene type: protein coding

About Sptssb

Summary

Contributes to serine C-palmitoyltransferase activity. Acts upstream of or within ceramide biosynthetic process; endoplasmic reticulum organization; and regulation of serine C-palmitoyltransferase activity. Part of serine C-palmitoyltransferase complex. Is expressed in central nervous system; eye; genitourinary system; and gut. Orthologous to human SPTSSB (serine palmitoyltransferase small subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Sptssb Products(3)

mRNA Protein Name
NM_001164210.2 NP_001157682.1 serine palmitoyltransferase small subunit B isoform a
NM_001286959.1 NP_001273888.1 serine palmitoyltransferase small subunit B isoform b
NM_133675.3 NP_598436.1 serine palmitoyltransferase small subunit B isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
contributes to serine C-palmitoyltransferase activity IDA
IDA: Inferred from direct assay
26438849 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
26438849 MGI
acts upstream of or within endoplasmic reticulum organization IMP
IMP: Inferred from mutant phenotype
26438849 MGI
acts upstream of or within regulation of serine C-palmitoyltransferase activity IMP
IMP: Inferred from mutant phenotype
26438849 MGI
acts upstream of or within sphingolipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
26438849 MGI
Cellular Component GO Annotation Evidence Reference Source
part of serine palmitoyltransferase complex IDA
IDA: Inferred from direct assay
26438849 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine palmitoyltransferase small subunit B

androgen down regulated in mouse prostate

small subunit of serine palmitoyltransferase B

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13740 SPTSSB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19531 Sptssb Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26026 Sptssb Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sptssb NCBI NCBI:165679