2. Gene
  3. Birc5 - baculoviral IAP repeat-containing 5 Gene

Birc5 - baculoviral IAP repeat-containing 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as AP14

Gene ID: 64041 | Gene type: protein coding

About Birc5

Summary

Predicted to enable several functions, including chaperone binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and protein dimerization activity. Involved in several processes, including cellular response to ethanol; cellular response to stem cell factor stimulus; and response to glucocorticoid. Located in apical plasma membrane; cytoplasm; and nucleus. Used to study endometriosis and pulmonary hypertension. Biomarker of acute pancreatitis (multiple); artery disease (multiple); congestive heart failure; high grade glioma; and stomach carcinoma. Human ortholog(s) of this gene implicated in prostate Cancer and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5). [provided by Alliance of Genome Resources, Apr 2022]

Birc5 Products(1)

mRNA Protein Name
NM_022274.2 NP_071610.2 baculoviral IAP repeat-containing protein 5
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to ethanol IEP
IEP: Inferred from expression pattern
20610854 RGD
involved in cellular response to stem cell factor stimulus IEP
IEP: Inferred from expression pattern
15130521 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
12833149 RGD
involved in positive regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
18332262 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
17112829 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
17112829 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17727822 RGD
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17982126 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

baculoviral IAP repeat-containing protein 5

apoptosis inhibitor survivin

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-173025 Nurr1 agonist 12 Agonist / Unkown
HY-RS01513 BIRC5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17902 Birc5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24371 Birc5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Birc5 NCBI NCBI:332
Mus musculus Birc5 NCBI NCBI:11799