2. Gene
  3. Vapb - VAMP associated protein B and C Gene

Vapb - VAMP associated protein B and C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as VAP-B; VAMP-B

Gene ID: 60431 | Gene type: protein coding

About Vapb

Summary

Predicted to enable several functions, including FFAT motif binding activity; protein dimerization activity; and tubulin binding activity. Predicted to be involved in several processes, including IRE1-mediated unfolded protein response; endoplasmic reticulum organization; and modulation by host of viral genome replication. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be active in endoplasmic reticulum membrane and plasma membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 8; autosomal dominant adult-onset proximal spinal muscular atrophy; and spinal muscular atrophy. Orthologous to human VAPB (VAMP associated protein B and C). [provided by Alliance of Genome Resources, Apr 2022]

Vapb Products(1)

mRNA Protein Name
NM_021847.4 NP_068619.1 vesicle-associated membrane protein-associated protein B
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in endoplasmic reticulum IDA
IDA: Inferred from direct assay
30841933 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
30841933 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
30841933 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
30841933 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicle-associated membrane protein-associated protein B

VAMP (vesicle-associated membrane protein)-associated protein B and C

VAMP-associated protein B

vesicle-associated membrane protein, associated protein B and C

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15603 VAPB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18156 Vapb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24630 Vapb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vapb NCBI NCBI:9217