2. Gene
  3. Adam15 - ADAM metallopeptidase domain 15 Gene

Adam15 - ADAM metallopeptidase domain 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as MDC15; tMDCVI

Gene ID: 57025 | Gene type: protein coding

About Adam15

Summary

Predicted to enable SH3 domain binding activity; Integrin binding activity; and metallopeptidase activity. Involved in male gonad development; response to hypobaric hypoxia; and tissue regeneration. Predicted to be located in cell surface and extracellular exosome. Predicted to be active in extracellular space. Orthologous to human ADAM15 (ADAM metallopeptidase domain 15). [provided by Alliance of Genome Resources, Apr 2022]

Adam15 Products(3)

mRNA Protein Name
NM_001399128.1 NP_001386057.1 disintegrin and metalloproteinase domain-containing protein 15 isoform 1 precursor
NM_001399129.1 NP_001386058.1 disintegrin and metalloproteinase domain-containing protein 15 isoform 2 precursor
NM_020308.2 NP_064704.1 disintegrin and metalloproteinase domain-containing protein 15 isoform 3 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in male gonad development IEP
IEP: Inferred from expression pattern
12815633 RGD
involved in response to hypobaric hypoxia IEP
IEP: Inferred from expression pattern
22230263 RGD
involved in tissue regeneration IEP
IEP: Inferred from expression pattern
11102971 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 15

ADAM 15

CRII-7

MDC-15

a disintegrin and metallopeptidase domain 15 (metargidin)

a disintegrin and metalloproteinase domain 15 (metargidin)

metalloprotease RGD disintegrin protein

metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00270 ADAM15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18692 Adam15 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25179 Adam15 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam15 NCBI NCBI:8751
Mus musculus Adam15 NCBI NCBI:11490