2. Gene
  3. Cib2 - calcium and integrin binding family member 2 Gene

Cib2 - calcium and integrin binding family member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as KIP2; KIP 2; 2810434I23Rik

Gene ID: 56506 | Gene type: protein coding

About Cib2

Summary

Enables calcium ion binding activity and Integrin binding activity. Involved in calcium ion homeostasis and photoreceptor cell maintenance. Located in several cellular components, including muscle tendon junction; photoreceptor inner segment; and sarcolemma. Is expressed in several structures, including central nervous system; gut; inner ear; integumental system; and skeletal musculature. Used to study autosomal recessive nonsyndromic deafness 48. Human ortholog(s) of this gene implicated in Usher syndrome type 1J and autosomal recessive nonsyndromic deafness 48. Orthologous to human CIB2 (calcium and Integrin binding family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cib2 Products(1)

mRNA Protein Name
NM_019686.6 NP_062660.1 calcium and integrin-binding family member 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
18611855 MGI
enables integrin binding IPI
IPI: Inferred from physical interaction
18611855 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
38228630 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
18611855 MGI
Biological Process GO Annotation Evidence Reference Source
involved in calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
23023331 MGI
involved in photoreceptor cell maintenance IDA
IDA: Inferred from direct assay
23023331 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
23023331 MGI
located in muscle tendon junction IDA
IDA: Inferred from direct assay
18611855 MGI
located in neuromuscular junction IDA
IDA: Inferred from direct assay
18611855 MGI
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
23023331 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
23023331 MGI
located in sarcolemma IDA
IDA: Inferred from direct assay
18611855 MGI
located in stereocilium IDA
IDA: Inferred from direct assay
23023331 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium and integrin-binding family member 2

calcium binding protein Kip2

kinase-interacting protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02707 CIB2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19884 Cib2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26384 Cib2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cib2 NCBI NCBI:10518