2. Gene
  3. GDPD2 - glycerophosphodiester phosphodiesterase domain containing 2 Gene

GDPD2 - glycerophosphodiester phosphodiesterase domain containing 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GDE3; OBDPF

Gene ID: 54857 | Gene type: protein coding

About GDPD2

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:70,423,314-70,433,381 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues and 5 paralogues. Biased expression in spleen (RPKM 25.5), skin (RPKM 21.4) and 4 other tissues.

Summary

This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

GDPD2 Products(4)

mRNA Protein Name
NM_001171191.2 NP_001164662.1 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 3
NM_001171192.2 NP_001164663.1 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 1
NM_001171193.2 NP_001164664.1 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 3
NM_017711.4 NP_060181.2 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 2

GDPD2 Protein Structure

GDPD

GDPD: Glycerophosphoryl diester phosphodiesterase family (229 - 359)

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  • 539 a.a.
Protein Preferred Names Protein Names

glycerophosphoinositol inositolphosphodiesterase GDPD2

glycerophosphodiester phosphodiesterase 3

Related Diseases

Diseases Alias
Junctional Epidermolysis Bullosa Non-Herlitz Type

Junctional Epidermolysis Bullosa, Non-Herlitz Type

Gabeb

Generalized Atrophic Benign Epidermolysis Bullosa

Generalized Junctional Epidermolysis Bullosa, Non-Herlitz Type

Jeb-Nh Gen

Jen-Nh

Junctional Epidermolysis Bullosa Generalisata Mitis

Junctional Epidermolysis Bullosa, Disentis Type

Epidermolysis Bullosa, Junctional, Non-Herlitz Type
Lynch Syndrome I

Lynch Syndrome 1

Colorectal Cancer, Hereditary Nonpolyposis, Type 1

HNPCC1

Fcc1

Lynch Syndrome Ii

Colon Cancer, Familial Nonpolyposis, Type 1

Coca1

Familial Nonpolyposis Colon Cancer Type 1

Hereditary Nonpolyposis Colorectal Cancer Type 1

Hereditary Non-Polyposis Colorectal Cancer 1

Hereditary Non-Polyposis Colorectal Cancer 3

Hnpcc3

Lynch Cancer Family Syndrome

Lynch Syndrome

Lynch Syndrome Type I

Lynch Syndrome Type Ii

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 1

Hereditary Nonpolyposis Colorectal Cancer

Colorectal Cancer, Hereditary Nonpolyposis, Type 3

Hereditary Non-Polyposis Colon Cancer Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05363 GDPD2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GDPD2 MGD MGI:1918834
Felis catus GDPD2 VGNC VGNC:62508
Bos taurus GDPD2 VGNC VGNC:29311
Rattus norvegicus GDPD2 RGD RGD:1560780
Canis familiaris GDPD2 VGNC VGNC:41167
Macaca mulatta GDPD2 VGNC VGNC:72787