2. Gene
  3. Cfhr2 - complement factor H-related 2 Gene

Cfhr2 - complement factor H-related 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FHR-B; Cfhrb_4/2

Gene ID: 545366 | Gene type: protein coding

About Cfhr2

Summary

Enables complement component C3b binding activity and heparin binding activity. Predicted to be involved in regulation of complement activation. Located in extracellular space. Human ortholog(s) of this gene implicated in age related macular degeneration 1 and atypical hemolytic-uremic syndrome. Orthologous to several human genes including CFHR3 (Complement Factor H Related 3). [provided by Alliance of Genome Resources, Apr 2022]

Cfhr2 Products(1)

mRNA Protein Name
NM_001025575.2 NP_001020746.1 complement factor H-related protein B precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables complement component C3b binding IPI
IPI: Inferred from physical interaction
17028856 MGI
enables heparin binding IDA
IDA: Inferred from direct assay
17028856 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
17028856 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement factor H-related protein B

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02563 CFHR2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20376 Cfhr2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26886 Cfhr2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cfhr2 NCBI NCBI:3080