Lsr - lipolysis stimulated lipoprotein receptor Gene

Mus musculus

Also known as ILDR3; Lisch7

Gene ID: 54135 | Gene type: protein coding

About Lsr

Summary

Predicted to enable lipoprotein particle receptor activity and low-density lipoprotein particle binding activity. Involved in several processes, including establishment of blood-brain barrier; establishment of skin barrier; and tricellular tight junction assembly. Acts upstream of or within protein localization to tricellular tight junction. Located in plasma membrane and tricellular tight junction. Is expressed in several structures, including alimentary system; genitourinary system; limb; liver; and respiratory system. Orthologous to human LSR (lipolysis stimulated lipoprotein receptor). [provided by Alliance of Genome Resources, Apr 2022]

Lsr Products(3)

mRNA	Protein	Name
NM_001164184.1	NP_001157656.1	lipolysis-stimulated lipoprotein receptor isoform 2 precursor
NM_001164185.1	NP_001157657.1	lipolysis-stimulated lipoprotein receptor isoform 3 precursor
NM_017405.2	NP_059101.1	lipolysis-stimulated lipoprotein receptor isoform 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	23239027	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in epithelial structure maintenance	IDA IDA: Inferred from direct assay	23239027	MGI
involved in establishment of blood-brain barrier	IMP IMP: Inferred from mutant phenotype	25753034	MGI
involved in establishment of skin barrier	IDA IDA: Inferred from direct assay	21245199	MGI
involved in liver development	IMP IMP: Inferred from mutant phenotype	15265030	MGI
involved in protein localization to tricellular tight junction	IMP IMP: Inferred from mutant phenotype	21245199	MGI
involved in tricellular tight junction assembly	IDA IDA: Inferred from direct assay	21245199	MGI
involved in tricellular tight junction assembly	IMP IMP: Inferred from mutant phenotype	22671589	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	15265030	MGI
located in tight junction	IDA IDA: Inferred from direct assay	23239027	MGI
located in tricellular tight junction	IDA IDA: Inferred from direct assay	21245199	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

lipolysis-stimulated lipoprotein receptor

angulin-3	lipolysis stimulated receptor
liver-specific bHLH-Zip transcription factor	liver-specific gene on mouse chromosome 7 protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07865	LSR Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21285	Lsr Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lsr	NCBI	NCBI:51599

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