2. Gene
  3. MRPS16 - mitochondrial ribosomal protein S16 Gene

MRPS16 - mitochondrial ribosomal protein S16 Gene

  • Gene
  • Protein
  • Agent
Homo sapiens (human)

Also known as S16mt; bS16m; COXPD2; RPMS16; CGI-132; MRP-S16

Gene ID: 51021 | Gene type: protein coding

About MRPS16

Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described. [provided by RefSeq, Jul 2008]

MRPS16 Products(1)

mRNA Protein Name
XM_054365976.1 XP_054221951.1 small ribosomal subunit protein bS16m isoform X1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19945174 GOA
Cellular Component GO Annotation Evidence Reference Source
part of mitochondrial small ribosomal subunit IDA
IDA: Inferred from direct assay
11279123 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

small ribosomal subunit protein bS16m

28S ribosomal protein S16, mitochondrial

mitochondrial small ribosomal subunit protein bS16m

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16303 MRPS16 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16329 Mrps16 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16333 Mrps16 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown