2. Gene
  3. Scly - selenocysteine lyase Gene

Scly - selenocysteine lyase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SCL; Scly1; Scly2; 9830169H08; A930015N15Rik

Gene ID: 50880 | Gene type: protein coding

About Scly

Summary

Predicted to enable several functions, including protein homodimerization activity; selenocysteine lyase activity; and vitamin B6 binding activity. Acts upstream of or within several processes, including negative regulation of cellular response to oxidative stress; response to insulin; and selenium compound metabolic process. Predicted to be located in Golgi apparatus. Predicted to be part of catalytic complex. Is expressed in alimentary system; liver; and nervous system. Orthologous to human SCLY (selenocysteine lyase). [provided by Alliance of Genome Resources, Apr 2022]

Scly Products(1)

mRNA Protein Name
NM_016717.3 NP_057926.2 selenocysteine lyase
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within lipid metabolic process IMP
IMP: Inferred from mutant phenotype
22890841 MGI
acts upstream of or within negative regulation of cellular response to oxidative stress IMP
IMP: Inferred from mutant phenotype
22890841 MGI
acts upstream of or within response to insulin IMP
IMP: Inferred from mutant phenotype
22890841 MGI
acts upstream of or within selenium compound metabolic process IMP
IMP: Inferred from mutant phenotype
22890841 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

selenocysteine lyase

mSCL

selenocysteine lyase

Selenocysteine reductase

selenocysteine reductase

Related Agents

Approval
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0361 Aspartame 99.90% Unkown
HY-17474 Parecoxib Inhibitor 99.29% Yes
HY-132587 Fitusiran Inhibitor 94.68% Unkown
HY-17474A Parecoxib Sodium Inhibitor 99.94% Yes
HY-B0561R Spironolactone (Standard) 98.55% Unkown
HY-B0318A Metronidazole hydrochloride / Unkown
HY-B0455AR Lomefloxacin (Standard) Inhibitor / Unkown
HY-B0455B Lomefloxacin (aspartate) Inhibitor / Unkown
HY-B0455A Lomefloxacin Inhibitor / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99590 Sotatercept 99.61% Unkown
Clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-132257 Rovalpituzumab tesirine Inhibitor 97.47% Phase 3
HY-136657 SC-43 99.01% Phase 2
HY-16012A Domatinostat 99.34% Phase 2
HY-16012 Domatinostat tosylate 99.66% Phase 2
HY-14718 Resminostat Inhibitor 99.84% Phase 2
HY-106395 Telinavir Inhibitor 98.16% Phase 2
HY-100934 SC-9 Activator / Phase 2
HY-19500 SC-75416 Inhibitor / Phase 2
HY-19897 4SC-203 Inhibitor 98.98% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99886 Pexelizumab Inhibitor / Phase 3
Pre-clinical Phase
Bioactive Molecules (131)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18749 SC79 Activator ≥98.0% Unkown
HY-10496 SC75741 Inhibitor 99.51% Unkown
HY-107410 SC-26196 Inhibitor 99.66% Unkown
HY-145799 5A2-SC8 Chemical 99.48% Unkown
HY-148559 4A3-SC8 99.21% Unkown
HY-15614 SC144 99.48% Unkown
HY-59105 SC-560 Inhibitor 99.79% Unkown
HY-13802 SC-514 Inhibitor 99.89% Unkown
HY-103226 SC-57461A Inhibitor 99.93% Unkown
HY-145758 FEN1-IN-SC13 Inhibitor 98.21% Unkown
HY-19832 SC66 99.65% Unkown
HY-124876 SynuClean-D Inhibitor 99.89% Unkown
HY-126681 SC-VC-PAB-MMAE 95.91% Unkown
HY-15614A SC144 hydrochloride 98.98% Unkown
HY-161409 SC912 99.13% Unkown
HY-W010983 SC-236 99.59% Unkown
HY-Y0079S D-Phenylalanine-d5 99.87% Unkown
HY-P0323A GP(33-41) TFA Inhibitor 99.62% Unkown
HY-W591424 m-PEG-NHS ester (MW 2000) ≥98.0% Unkown
HY-18086 TCS PIM-1 1 Inhibitor 98.40% Unkown
HY-144880 SC209 Inhibitor 99.52% Unkown
HY-131236 EBNA1-IN-SC7 99.92% Unkown
HY-100931 SC-10 Activator 98.65% Unkown
HY-129982 SC-435 99.14% Unkown
HY-108563A SC 51089 free base Antagonist 98.60% Unkown
HY-155656 Anti-inflammatory agent 49 Inhibitor 98.26% Unkown
HY-164373 SC428 ≥98.0% Unkown
HY-170554 ABBV-706 99.63% Unkown
HY-108562 SC-51322 Antagonist 98.90% Unkown
HY-158031 PLK1/BRD4-IN-5 99.55% Unkown
HY-124858 SC99 98.90% Unkown
HY-W013164 SC-58125 Inhibitor 99.92% Unkown
HY-132306 CCF0058981 Inhibitor 98.02% Unkown
HY-138865 BiCAPPA Inhibitor 98.35% Unkown
HY-102065 SC-19220 Antagonist 99.71% Unkown
HY-148404 p53 Activator 5 Activator 98.43% Unkown
HY-W028047 JFD01307SC Inhibitor ≥98.0% Unkown
HY-145799A 5A2-SC8 TFA Chemical 98.56% Unkown
HY-W004297 1-Nonadecanol 99.16% Unkown
HY-118827 Vedaprofen Inhibitor 99.42% Unkown
HY-148194 SC239 99.97% Unkown
HY-114857 Clofencet 98.62% Unkown
HY-120113 SC-2001 99.37% Unkown
HY-126693 SC-VC-PAB-DM1 97.04% Unkown
HY-148402 p53 Activator 3 Activator 98.35% Unkown
HY-B0561S Spironolactone-d7 99.96% Unkown
HY-B0561S1 Spironolactone-d3 99.82% Unkown
HY-N9319 Fulvotomentoside A 98.94% Unkown
HY-47968 SC209 intermediate-1 ≥96.0% Unkown
HY-Y0079S1 D-Phenylalanine-d8 98.28% Unkown
HY-106395A (Rac)-Telinavir Inhibitor / Unkown
HY-108563 SC 51089 Antagonist / Unkown
HY-148528 SC-VC-PAB-N-Me-L-Ala-Maytansinol 98.16% Unkown
HY-B0455S Lomefloxacin-d5 hydrochloride 99.88% Unkown
HY-W009934 2-Phenyl-2-(2-pyridyl)acetonitrile 99.97% Unkown
HY-U00129 SC57666 Inhibitor 98.94% Unkown
HY-U00232 Bidisomide 99.62% Unkown
HY-100857 PrPSc-IN-1 / Unkown
HY-B0361S1 Aspartame-d5 / Unkown
HY-14398GL Celecoxib (GMP Like) Inhibitor / Unkown
HY-14908A Vidofludimus hemicalcium / Unkown
HY-105052 SC 34301 / Unkown
HY-112739 SC-41930 Agonist / Unkown
HY-115360 IND45193 Inhibitor / Unkown
HY-117896 SC-50605 Antagonist / Unkown
HY-118795 SC-22716 Inhibitor / Unkown
HY-120776 SC-51316 Antagonist / Unkown
HY-120794 SC-67655 / Unkown
HY-121598 Actisomide Inducer / Unkown
HY-122134 SC-58272 Inhibitor / Unkown
HY-123014 (Rac)-SC-45694 Agonist / Unkown
HY-123229 Ropizine / Unkown
HY-124775 (S)-C33 Inhibitor 99.46% Unkown
HY-125494 Droxinavir hydrochloride Inhibitor / Unkown
HY-126667 SC-Val-Cit-PAB / Unkown
HY-129782 SC-55858 / Unkown
HY-139678 SC13 Agonist / Unkown
HY-156271 Tubulin polymerization-IN-52 Inhibitor / Unkown
HY-162791 (1s,4s)-C1-Piperidine-C1-cyclohexane-C1 / Unkown
HY-168730 Anticancer agent 259 Modulator / Unkown
HY-172133 HDAC3-IN-6 / Unkown
HY-172887 Kv7.2/Kv7.3 activator-2 Activator / Unkown
HY-172944 GPR40 Activator 3 Activator / Unkown
HY-17474AS Parecoxib-d5 sodium Inhibitor / Unkown
HY-17474S Parecoxib-d3 Inhibitor / Unkown
HY-174808 SC691 Inhibitor / Unkown
HY-176065 Nav1.2-IN-1 Inhibitor / Unkown
HY-400056 SC209 intermediate-2 99.60% Unkown
HY-B0561S2 Spironolactone-d3-1 / Unkown
HY-N12871 Floramanoside D Inhibitor / Unkown
HY-N15703 Norisocorydine / Unkown
HY-P10827 PIC1 PA Inhibitor / Unkown
HY-P3326 Targeting the bacterial sliding clamp peptide 46 Inhibitor / Unkown
HY-RS12473 SC5D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12514 SCLY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W777079 Valdecoxib-13C2,15N / Unkown
HY-112333 SC-68376 Inhibitor / Unkown
HY-117717 (Rac)-SC-31391 Activator / Unkown
HY-118827S Vedaprofen-d3 Inhibitor / Unkown
HY-120045A DuP 747 hydrochloride / Unkown
HY-120550 RS 49676 Inhibitor / Unkown
HY-120586 SC-46944 Inhibitor / Unkown
HY-122288 SC 28538 Inhibitor / Unkown
HY-123156 SC-23110 Inhibitor / Unkown
HY-123354 SC 44914 Inhibitor / Unkown
HY-123747 SC-53116 Agonist / Unkown
HY-123747A SC-53116 hydrochloride Agonist / Unkown
HY-137089 Azacosterol dihydrochloride Inhibitor / Unkown
HY-137225 HTS07944 / Unkown
HY-157405 DENV-IN-11 Inhibitor / Unkown
HY-163631 Antibacterial agent 218 Inhibitor / Unkown
HY-164525 SD-7300 Inhibitor / Unkown
HY-168776 (S)-C12-200 / Unkown
HY-170520 Antibiofilm agent-14 Inhibitor / Unkown
HY-172411 GLP-1R agonist 29 Agonist / Unkown
HY-172536 m-PEG-NHS ester (MW 30000) / Unkown
HY-17474S1 Parecoxib-d5 Inhibitor / Unkown
HY-177069 4A3-SC7 / Unkown
HY-B0361S Aspartame-d3 / Unkown
HY-N12164 Linearmycin B Inhibitor / Unkown
HY-N14006 Louisianin D / Unkown
HY-N14139 Dioxamycin Inhibitor / Unkown
HY-N14632 Louisianin A / Unkown
HY-N14633 Louisianin B / Unkown
HY-N14634 Louisianin C / Unkown
HY-RS19952 Scly Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26454 Scly Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W703540 Deracoxib-d4 / Unkown
HY-P0323 GP(33-41) Inhibitor / Unkown
HY-U00200 Dicirenone Antagonist / Unkown
HY-U00239 SC58451 Inhibitor / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991041 Anti-SEZ6 Antibody (SC17) 99.37% Unkown
HY-P990664 Anti-Melanotransferrin/CD228 Antibody / Unkown
HY-P99506 Tamrintamab 98.51% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scly NCBI NCBI:51540