2. Anti-infection
  3. EBV
  4. EBNA1-IN-SC7

EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research.

For research use only. We do not sell to patients.

EBNA1-IN-SC7 Chemical Structure

EBNA1-IN-SC7 Chemical Structure

CAS No. : 324022-08-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
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Based on 1 publication(s) in Google Scholar

EBNA1-IN-SC7 Related Antibodies

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Description

EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research[1].

In Vitro

EBNA1-IN-SC7 (compound SC7) (5 µM) can completely block transcriptional activation of EBNA1 and show a 60% inhibition of Zta (EBV-encoded b-zip DNA binding protein) trans-activation in HEK293T cells[2].
EBNA1-IN-SC7 (compound SC7) (10 µM, 6 days) has no significant effect on EBV genome copy number of Raji Burkitt lymphoma cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EBNA1-IN-SC7 Related Antibodies
Molecular Weight

462.31

Formula

C20H16BrNO5S
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CC(N(C1=CC=C(OC(C)=O)C(Br)=C1)S(=O)(C2=CC=C3C=CC=CC3=C2)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (270.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1631 mL 10.8153 mL 21.6305 mL
5 mM 0.4326 mL 2.1631 mL 4.3261 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.92%

SDS (393 KB)

COA (255 KB) HNMR (275 KB) LCMS (95 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1631 mL 10.8153 mL 21.6305 mL 54.0763 mL
5 mM 0.4326 mL 2.1631 mL 4.3261 mL 10.8153 mL
10 mM 0.2163 mL 1.0815 mL 2.1631 mL 5.4076 mL
15 mM 0.1442 mL 0.7210 mL 1.4420 mL 3.6051 mL
20 mM 0.1082 mL 0.5408 mL 1.0815 mL 2.7038 mL
25 mM 0.0865 mL 0.4326 mL 0.8652 mL 2.1631 mL
30 mM 0.0721 mL 0.3605 mL 0.7210 mL 1.8025 mL
40 mM 0.0541 mL 0.2704 mL 0.5408 mL 1.3519 mL
50 mM 0.0433 mL 0.2163 mL 0.4326 mL 1.0815 mL
60 mM 0.0361 mL 0.1803 mL 0.3605 mL 0.9013 mL
80 mM 0.0270 mL 0.1352 mL 0.2704 mL 0.6760 mL
100 mM 0.0216 mL 0.1082 mL 0.2163 mL 0.5408 mL
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EBNA1-IN-SC7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EBNA1-IN-SC7324022-08-4EBVEpstein-Barr VirusEBNA1EBV-associated cancersInhibitorinhibitorinhibit

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