2. Gene
  3. Acsl4 - acyl-CoA synthetase long-chain family member 4 Gene

Acsl4 - acyl-CoA synthetase long-chain family member 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ACS4; Facl4; Lacs4; 9430020A05Rik

Gene ID: 50790 | Gene type: protein coding

About Acsl4

Summary

Enables long-chain fatty acid-CoA Ligase activity. Acts upstream of or within embryonic process involved in female pregnancy and neuron differentiation. Located in mitochondrion. Is expressed in several structures, including alimentary system; integumental system; limb mesenchyme; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability 63. Orthologous to human ACSL4 (acyl-CoA synthetase long chain family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Acsl4 Products(3)

mRNA Protein Name
NM_001033600.1 NP_001028772.1 long-chain-fatty-acid--CoA ligase 4 isoform 2
NM_019477.3 NP_062350.3 long-chain-fatty-acid--CoA ligase 4 isoform 2
NM_207625.2 NP_997508.1 long-chain-fatty-acid--CoA ligase 4 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
23159612 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within embryonic process involved in female pregnancy IMP
IMP: Inferred from mutant phenotype
11409893 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
23159612 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

long-chain-fatty-acid--CoA ligase 4

LACS 4

arachidonate--CoA ligase

fatty acid-Coenzyme A ligase, long chain 4

long-chain acyl-CoA synthetase 4

mACS4

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16244 Acsl4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00202 ACSL4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-115701 1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe Inducer / Unkown
HY-155851 Lepadin E / Unkown
HY-155852 Lepadin H Inducer / Unkown
HY-RS16556 Acsl4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acsl4 NCBI NCBI:2182