2. Gene
  3. Grb10 - growth factor receptor bound protein 10 Gene

Grb10 - growth factor receptor bound protein 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1566234

Gene ID: 498416 | Gene type: protein coding

About Grb10

Summary

Enables Insulin Receptor binding activity. Involved in Insulin Receptor signaling pathway; negative regulation of glycogen biosynthetic process; and positive regulation of phosphorylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Orthologous to human GRB10 (growth factor receptor bound protein 10). [provided by Alliance of Genome Resources, Apr 2022]

Grb10 Products(2)

mRNA Protein Name
NM_001401403.1 NP_001388332.1 growth factor receptor-bound protein 10 isoform 1
NM_001401404.1 NP_001388333.1 growth factor receptor-bound protein 10 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables insulin receptor binding IDA
IDA: Inferred from direct assay
11223174 RGD
Biological Process GO Annotation Evidence Reference Source
involved in insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
11223174 RGD
involved in negative regulation of glycogen biosynthetic process IDA
IDA: Inferred from direct assay
11223174 RGD
involved in positive regulation of phosphorylation IDA
IDA: Inferred from direct assay
11223174 RGD
involved in response to insulin IDA
IDA: Inferred from direct assay
11223174 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth factor receptor-bound protein 10

GRB10 adapter protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05778 GRB10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22539 Grb10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29059 Grb10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grb10 NCBI NCBI:2887