2. Gene
  3. Foxl2 - forkhead box L2 Gene

Foxl2 - forkhead box L2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 367152 | Gene type: protein coding

About Foxl2

Summary

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; Estrogen receptor binding activity; and ubiquitin conjugating enzyme binding activity. Predicted to be involved in several processes, including apoptotic DNA fragmentation; extraocular skeletal muscle development; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to act upstream of or within several processes, including positive regulation of gonadotropin secretion; regulation of transcription by RNA polymerase II; and reproductive structure development. Predicted to be located in Flemming body and nucleoplasm. Human ortholog(s) of this gene implicated in blepharophimosis, ptosis, and epicanthus inversus syndrome and primary ovarian insufficiency 3. Orthologous to human FOXL2 (forkhead box L2). [provided by Alliance of Genome Resources, Apr 2022]

Foxl2 Products(1)

mRNA Protein Name
XM_003750571.5 XP_003750619.1 forkhead box protein L2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
23567549 RGD
involved in response to human chorionic gonadotropin IEP
IEP: Inferred from expression pattern
23239112 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22777679 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

forkhead box protein L2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05062 FOXL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20023 Foxl2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26526 Foxl2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Foxl2 NCBI NCBI:668