1. Gene
  2. Trim72 - tripartite motif containing 72 Gene

Trim72 - tripartite motif containing 72 Gene

Rattus norvegicus

Also known as RGD1562778

Gene ID: 365377 | Gene type: protein coding

About Trim72

Summary

Predicted to enable several functions, including phosphatidylserine binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; plasma membrane repair; and protein homooligomerization. Predicted to act upstream of or within negative regulation of Insulin Receptor signaling pathway; negative regulation of insulin-like growth factor receptor signaling pathway; and negative regulation of myotube differentiation. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in cytoplasm and sarcolemma. Orthologous to human TRIM72 (tripartite motif containing 72). [provided by Alliance of Genome Resources, Apr 2022]

Trim72 Products(1)

mRNA Protein Name
NM_001077675.1 NP_001071143.1 tripartite motif-containing protein 72
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables mitogen-activated protein kinase kinase kinase binding IPI
IPI: Inferred from physical interaction
30760025 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tripartite motif-containing protein 72

mg53

mitsugumin-53

tripartite motif containing 72, E3 ubiquitin protein ligase

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim72 NCBI NCBI:493829