Blk - BLK proto-oncogene, Src family tyrosine kinase Gene

Rattus norvegicus

Gene ID: 364403 | Gene type: protein coding

About Blk

Summary

Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; negative regulation of leukocyte proliferation; and regulation of leukocyte apoptotic process. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 11 and systemic lupus erythematosus. Orthologous to human Blk (Blk proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Blk Products(1)

mRNA	Protein	Name
NM_001025751.1	NP_001020922.1	tyrosine-protein kinase Blk

Protein Preferred Names

Protein Names

tyrosine-protein kinase Blk

B lymphoid tyrosine kinase

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-157442	GLPG3312	Inhibitor	98.57%	Phase 1

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-118105	RK-20448	Inhibitor	99.38%	Unkown
HY-120622	BMS-243117	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Blk	NCBI	NCBI:640

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