2. Gene
  3. Itgb8 - integrin subunit beta 8 Gene

Itgb8 - integrin subunit beta 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362800 | Gene type: protein coding

About Itgb8

Summary

Enables signaling receptor binding activity. Predicted to be involved in several processes, including integrin-mediated signaling pathway; regulation of gene expression; and vasculogenesis. Predicted to act upstream of or within several processes, including Langerhans cell differentiation; ganglioside metabolic process; and hard palate development. Predicted to be part of Integrin alphav-beta8 complex. Predicted to be active in cell surface and focal adhesion. Orthologous to human ITGB8 (Integrin subunit beta 8). [provided by Alliance of Genome Resources, Apr 2022]

Itgb8 Products(1)

mRNA Protein Name
NM_001401817.1 NP_001388746.1 integrin beta-8 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
21969374 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin beta-8

integrin, beta 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06972 ITGB8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17983 Itgb8 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24454 Itgb8 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgb8 NCBI NCBI:3696
Mus musculus Itgb8 NCBI NCBI:320910
Macaca mulatta Itgb8 NCBI NCBI:707247