1. Gene
  2. Adam32 - a disintegrin and metallopeptidase domain 32 Gene

Adam32 - a disintegrin and metallopeptidase domain 32 Gene

Mus musculus
Gene ID: 353188 | Gene type: protein coding

About Adam32

Summary

This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene was found to be expressed predominantly in the pachytene spermatocytes, where the processed protein is localized to the sperm surface. This gene is located in a cluster of Other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]

Adam32 Products(4)

mRNA Protein Name
NM_001293693.1 NP_001280622.1 disintegrin and metalloproteinase domain-containing protein 32 isoform 2 precursor
NM_153397.2 NP_700446.2 disintegrin and metalloproteinase domain-containing protein 32 isoform 1 preproprotein
NM_001293693.1 NP_001280622.1 disintegrin and metalloproteinase domain-containing protein 32 isoform 2 precursor
NM_153397.2 NP_700446.2 disintegrin and metalloproteinase domain-containing protein 32 isoform 1 preproprotein
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in cell surface IDA
IDA: Inferred from direct assay
16407499 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 32

a disintegrin and metalloprotease domain 32

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam32 NCBI NCBI:203102