NME9 - NME/NM23 family member 9 Gene

Homo sapiens

Also known as NXL2; TXL2; TXL-2; TXNDC6; NM23-H9

Gene ID: 347736 | Gene type: protein coding

About NME9

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:138,261,436-138,329,851 (from NCBI)

This gene has 9 transcripts (splice variants), 193 orthologues and 8 paralogues. Ubiquitous expression in thyroid (RPKM 1.1), brain (RPKM 1.0) and 25 other tissues.

Summary

Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in dynein axonemal particle. [provided by Alliance of Genome Resources, Apr 2022]

NME9 Products(8)

mRNA	Protein	Name
NM_001349018.2	NP_001335947.1	thioredoxin domain-containing protein 6 isoform a
NM_001349020.2	NP_001335949.1	thioredoxin domain-containing protein 6 isoform c
NM_001349021.2	NP_001335950.1	thioredoxin domain-containing protein 6 isoform d
NM_001349022.2	NP_001335951.1	thioredoxin domain-containing protein 6 isoform e
NM_001349023.2	NP_001335952.1	thioredoxin domain-containing protein 6 isoform f
NM_001349024.2	NP_001335953.1	thioredoxin domain-containing protein 6 isoform g
NM_001349025.2	NP_001335954.1	thioredoxin domain-containing protein 6 isoform g
NM_178130.4	NP_835231.1	thioredoxin domain-containing protein 6 isoform b

NME9 Protein Structure

Thioredoxin

NDK

0
100
200
300
330 a.a.

Protein Preferred Names

Protein Names

thioredoxin domain-containing protein 6

NME gene family member 9

Related Diseases

Diseases

Alias

Ciliary Dyskinesia, Primary, 6

Primary Ciliary Dyskinesia 6	CILD6
Ics6	Immotile Cilia Syndrome 6
Dyskinesia, Ciliary, Primary, 6

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome	Kartagener Syndrome
Dextrocardia Bronchiectasis And Sinusitis	Pcd
Ciliary Motility Disorders	Ciliary Motility Disorder
Immotile Ciliary Syndrome	Ciliary Dyskinesia Primary
Ics	Polynesian Bronchiectasis
Dextrocardia-Bronchiectasis-Sinusitis Syndrome	Immotile Cilia Syndrome, Kartagener Type
Primary Ciliary Dyskinesia And Situs Inversus	Primary Ciliary Dyskinesia, Kartagener Type
Siewert Syndrome	Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09380	NME9 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	NME9	VGNC	VGNC:75228
Felis catus	NME9	VGNC	VGNC:63839
Mus musculus	NME9	MGD	MGI:4359686
Canis familiaris	NME9	VGNC	VGNC:43860
Bos taurus	NME9	VGNC	VGNC:32131
Rattus norvegicus	NME9	RGD	RGD:1564871

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