2. Gene
  3. Adamts3 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3 Gene

Adamts3 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1100001H14Rik; 6330442E02Rik

Gene ID: 330119 | Gene type: protein coding

About Adamts3

Summary

Enables peptidase activity. Acts upstream of or within in utero embryonic development and protein processing. Predicted to be located in extracellular space. Predicted to be active in extracellular matrix. Is expressed in embryo; footplate apical ectodermal ridge; and handplate apical ectodermal ridge. Human ortholog(s) of this gene implicated in Hennekam syndrome. Orthologous to human ADAMTS3 (ADAM metallopeptidase with thrombospondin type 1 motif 3). [provided by Alliance of Genome Resources, Apr 2022]

Adamts3 Products(2)

mRNA Protein Name
NM_001081401.2 NP_001074870.1 A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform 2 precursor
NM_177872.2 NP_808540.2 A disintegrin and metalloproteinase with thrombospondin motifs 3 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables peptidase activity IDA
IDA: Inferred from direct assay
16556917 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
27996060 MGI
acts upstream of or within protein processing IDA
IDA: Inferred from direct assay
16556917 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A disintegrin and metalloproteinase with thrombospondin motifs 3

ADAM metallopeptidase with thrombospondin type 1 motif, 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00301 ADAMTS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00303 ADAMTS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21980 Adamts3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28497 Adamts3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adamts3 NCBI NCBI:9508