2. Gene
  3. Ccbe1 - collagen and calcium binding EGF domains 1 Gene

Ccbe1 - collagen and calcium binding EGF domains 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1983; 4933426F18Rik; 9430093N24Rik

Gene ID: 320924 | Gene type: protein coding

About Ccbe1

Summary

Predicted to enable Collagen binding activity and protease binding activity. Involved in positive regulation of angiogenesis and positive regulation of lymphangiogenesis. Acts upstream of or within several processes, including lymphangiogenesis; positive regulation of endothelial cell migration; and respiratory system process. Predicted to be located in extracellular matrix and extracellular space. Predicted to be part of Collagen trimer. Is expressed in several structures, including anterior cardinal vein; branchial arch; embryo mesenchyme; heart; and intraembryonic coelom. Human ortholog(s) of this gene implicated in Hennekam syndrome. Orthologous to human CCBE1 (Collagen and calcium binding EGF domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Ccbe1 Products(1)

mRNA Protein Name
NM_178793.4 NP_848908.1 collagen and calcium-binding EGF domain-containing protein 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
21778431 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
24733830 MGI
acts upstream of or within lymph vessel development IMP
IMP: Inferred from mutant phenotype
24733830 MGI
acts upstream of or within lymphangiogenesis IMP
IMP: Inferred from mutant phenotype
21778431 MGI
acts upstream of lymphatic endothelial cell migration IMP
IMP: Inferred from mutant phenotype
21778431 MGI
involved in positive regulation of angiogenesis IDA
IDA: Inferred from direct assay
24552833 MGI
acts upstream of or within positive regulation of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
21778431 MGI
involved in positive regulation of lymphangiogenesis IDA
IDA: Inferred from direct assay
24552833 MGI
acts upstream of or within respiratory gaseous exchange by respiratory system IMP
IMP: Inferred from mutant phenotype
24733830 MGI
acts upstream of or within respiratory system process IMP
IMP: Inferred from mutant phenotype
24733830 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen and calcium-binding EGF domain-containing protein 1

full of fluid protein homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02022 CCBE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22418 Ccbe1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28941 Ccbe1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccbe1 NCBI NCBI:147372