2. Gene
  3. Phf8 - PHD finger protein 8 Gene

Phf8 - PHD finger protein 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1111; 9830141C09Rik

Gene ID: 320595 | Gene type: protein coding

About Phf8

Summary

Predicted to enable several functions, including Histone Demethylase activity; methylated histone binding activity; and transition metal ion binding activity. Predicted to be involved in G1/S transition of mitotic cell cycle; histone lysine demethylation; and regulation of gene expression. Predicted to act upstream of or within chromatin organization. Predicted to be located in nuclear membrane; nucleolus; and nucleoplasm. Is expressed in several structures, including brain; early conceptus; olfactory epithelium; ovary; and vibrissa follicle. Used to study syndromic X-linked intellectual disability Siderius type. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Siderius type. Orthologous to human PHF8 (PHD finger protein 8). [provided by Alliance of Genome Resources, Apr 2022]

Phf8 Products(2)

mRNA Protein Name
NM_001113354.1 NP_001106825.1 histone lysine demethylase PHF8 isoform b
NM_177201.5 NP_796175.1 histone lysine demethylase PHF8 isoform a
Protein Preferred Names Protein Names

histone lysine demethylase PHF8

[histone H3]-dimethyl-L-lysine(36) demethylase PHF8

[histone H3]-dimethyl-L-lysine(9) demethylase PHF8

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13643 Daminozide Inhibitor 99.79% Unkown
HY-153608 JHDM-IN-1 Inhibitor 97.60% Unkown
HY-RS10431 PHF8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18042 Phf8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24516 Phf8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Phf8 NCBI NCBI:23133