Tgif1 - TGFB-induced factor homeobox 1 Gene

Rattus norvegicus

Also known as Tfig; Tgif

Gene ID: 316742 | Gene type: protein coding

About Tgif1

Summary

Enables co-SMAD binding activity. Involved in cellular response to growth factor stimulus; negative regulation of gene expression; and response to xenobiotic stimulus. Located in nucleus. Biomarker of muscular atrophy. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 4. Orthologous to human TGIF1 (TGFB induced factor homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Tgif1 Products(1)

mRNA	Protein	Name
NM_001015020.1	NP_001015020.1	homeobox protein TGIF1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables co-SMAD binding	IPI IPI: Inferred from physical interaction	15153551	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to growth factor stimulus	IEP IEP: Inferred from expression pattern	15153551	RGD
involved in negative regulation of gene expression	IMP IMP: Inferred from mutant phenotype	18441095	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	12169274	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

homeobox protein TGIF1

TG interacting factor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14455	TGIF1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20113	Tgif1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26617	Tgif1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tgif1	NCBI	NCBI:7050

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