2. Gene
  3. Ttbk1 - tau tubulin kinase 1 Gene

Ttbk1 - tau tubulin kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1559518

Gene ID: 316229 | Gene type: protein coding

About Ttbk1

Summary

Predicted to enable protein kinase activity and Tau Protein binding activity. Predicted to be involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of microglial cell activation; and protein phosphorylation. Predicted to be located in several cellular components, including neuronal cell body; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human TTBK1 (tau tubulin kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ttbk1 Products(1)

mRNA Protein Name
NM_001271230.2 NP_001258159.1 tau-tubulin kinase 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
26323690 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tau-tubulin kinase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-134968 TTBK1-IN-1 Inhibitor 99.53% Unkown
HY-145313 TTBK1-IN-2 Inhibitor 99.91% Unkown
HY-134968A (R)-TTBK1-IN-1 Inhibitor 98.93% Unkown
HY-172542 TTBK1/2-IN-1 Inhibitor / Unkown
HY-172543 TTBK1/2-IN-2 Inhibitor / Unkown
HY-172544 TTBK1/2-IN-3 Inhibitor / Unkown
HY-172545 AMG28 Inhibitor / Unkown
HY-RS15193 TTBK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17713 Ttbk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21071 Ttbk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24178 Ttbk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttbk1 NCBI NCBI:84630