2. Gene
  3. Ttbk2 - tau tubulin kinase 2 Gene

Ttbk2 - tau tubulin kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 311349 | Gene type: protein coding

About Ttbk2

Summary

Predicted to enable Kinesin binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including hindbrain development; negative regulation of microtubule depolymerization; and negative regulation of protein localization to microtubule. Predicted to act upstream of or within several processes, including embryonic brain development; nervous system development; and positive regulation of non-motile cilium assembly. Predicted to be located in centriole; cytosol; and intermediate filament Cytoskeleton. Predicted to be active in several cellular components, including ciliary basal body; ciliary transition zone; and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK2 (tau tubulin kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ttbk2 Products(1)

mRNA Protein Name
NM_001107766.1 NP_001101236.1 tau-tubulin kinase 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
26323690 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tau-tubulin kinase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-172542 TTBK1/2-IN-1 Inhibitor / Unkown
HY-172543 TTBK1/2-IN-2 Inhibitor / Unkown
HY-172544 TTBK1/2-IN-3 Inhibitor / Unkown
HY-172545 AMG28 Inhibitor / Unkown
HY-RS15194 TTBK2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21071 Ttbk2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27588 Ttbk2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttbk2 NCBI NCBI:146057