2. Gene
  3. Tet2 - tet methylcytosine dioxygenase 2 Gene

Tet2 - tet methylcytosine dioxygenase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1311625

Gene ID: 310859 | Gene type: protein coding

About Tet2

Summary

Predicted to enable ferrous iron binding activity; methylcytosine dioxygenase activity; and zinc ion binding activity. Involved in response to organic cyclic compound. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system Cancer (multiple); hematologic Cancer (multiple); lung non-small cell carcinoma; and primary immunodeficiency disease. Orthologous to human TET2 (tet methylcytosine dioxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Tet2 Products(4)

mRNA Protein Name
XM_039103857.1 XP_038959785.1 methylcytosine dioxygenase TET2 isoform X1
XM_008761534.3 XP_008759756.1 methylcytosine dioxygenase TET2 isoform X2
XM_006233347.4 XP_006233409.1 methylcytosine dioxygenase TET2 isoform X1
XM_227694.9 XP_227694.5 methylcytosine dioxygenase TET2 isoform X3
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
25154389 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable methylcytosine dioxygenase TET2

methylcytosine dioxygenase TET2

tet oncogene family member 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111558 Bobcat339 Inhibitor 99.44% Unkown
HY-111558A Bobcat339 hydrochloride Inhibitor 99.59% Unkown
HY-402410 TETi76 Inhibitor 97.49% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tet2 NCBI NCBI:54790