2. Gene
  3. Kirrel1 - kirre like nephrin family adhesion molecule 1 Gene

Kirrel1 - kirre like nephrin family adhesion molecule 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Neph1; Kirrel

Gene ID: 310695 | Gene type: protein coding

About Kirrel1

Summary

Predicted to enable cell adhesion molecule binding activity and Myosin binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within excretion; negative regulation of protein phosphorylation; and positive regulation of actin filament polymerization. Located in cell projection membrane; cell-cell junction; and membrane raft. Human ortholog(s) of this gene implicated in nephrotic syndrome type 23. Orthologous to human KIRREL1 (kirre like nephrin family adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Kirrel1 Products(1)

mRNA Protein Name
NM_207606.2 NP_997489.2 kin of IRRE-like protein 1 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12646566 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell projection membrane IDA
IDA: Inferred from direct assay
12646566 RGD
located in cell-cell junction IDA
IDA: Inferred from direct assay
12646566 RGD
located in membrane raft IDA
IDA: Inferred from direct assay
21402783 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kin of IRRE-like protein 1

kin of IRRE like 1

kin of irregular chiasm-like protein 1

nephrin 1

nephrin-like protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07312 KIRREL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18317 Kirrel1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24795 Kirrel1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kirrel1 NCBI NCBI:55243
Mus musculus Kirrel1 NCBI