2. Gene
  3. Lamtor1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

Lamtor1 - late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as p18

Gene ID: 308869 | Gene type: protein coding

About Lamtor1

Summary

Predicted to enable GTPase binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in several processes, including Cholesterol homeostasis; positive regulation of intracellular signal transduction; and regulation of Cholesterol transport. Located in late endosome membrane and membrane raft. Orthologous to human LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and mTOR Activator 1). [provided by Alliance of Genome Resources, Apr 2022]

Lamtor1 Products(1)

mRNA Protein Name
NM_199102.1 NP_954533.1 ragulator complex protein LAMTOR1
Protein Preferred Names Protein Names

ragulator complex protein LAMTOR1

RhoA activator C11orf59 homolog

late endosomal/lysosomal adaptor and MAPK and MTOR activator 1

lipid raft adaptor protein p18

p27Kip1-releasing factor from RhoA

p27RF-Rho

Lamtor1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Lamtor1 Q6P791 Lamtor2 Mus musculus Q9JHS3
Anti Tag CoIP
19177150
Cross
Lamtor1 Q6P791 Lamtor2 Mus musculus Q9JHS3
Pull Down
19177150
Cross
Lamtor1 Q6P791 Lamtor3 Mus musculus O88653
Anti Tag CoIP
19177150
Cross
Lamtor1 Q6P791 Lamtor3 Mus musculus O88653
Pull Down
19177150
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-176166 PD-M6 Degrader / Unkown
HY-RS07513 LAMTOR1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20212 Lamtor1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26717 Lamtor1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lamtor1 NCBI NCBI:55004