Nectin2 - nectin cell adhesion molecule 2 Gene

Also known as Pvrl2

About Nectin2

Summary

Predicted to enable cell adhesion molecule binding activity and protein homodimerization activity. Predicted to be involved in several processes, including coreceptor-mediated virion attachment to host cell; homophilic cell adhesion via plasma membrane adhesion molecules; and positive regulation of immune response. Predicted to act upstream of or within several processes, including cilium organization; sperm mitochondrion organization; and spermatid nucleus differentiation. Predicted to be located in cell surface; cell-cell contact zone; and zonula adherens. Predicted to be active in apical junction complex and plasma membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Orthologous to human NECTIN2 (nectin cell adhesion molecule 2). [provided by Alliance of Genome Resources, Apr 2022]