2. Gene
  3. Adamts8 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 Gene

Adamts8 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as METH2; METH-2

Gene ID: 30806 | Gene type: protein coding

About Adamts8

Summary

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is expressed in mouse lung, heart and macrophage-rich areas of atherosclerotic plaques. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent aggrecanase enzyme. This gene is located adjacent to a related ADAMTS gene on chromosome 9. [provided by RefSeq, May 2016]

Adamts8 Products(2)

mRNA Protein Name
NM_001326292.1 NP_001313221.1 A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform 2
NM_013906.3 NP_038934.2 A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform 1 preproprotein
Protein Preferred Names Protein Names

A disintegrin and metalloproteinase with thrombospondin motifs 8

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS27128 Adamts8 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00308 ADAMTS8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20620 Adamts8 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adamts8 NCBI NCBI:11095