Nelfa - negative elongation factor complex member A Gene

Rattus norvegicus

Also known as Whsc2

Gene ID: 305455 | Gene type: protein coding

About Nelfa

Summary

Enables chromatin binding activity. Involved in positive regulation of histone H3-K4 methylation and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nuclear body. Predicted to be part of NELF complex. Orthologous to human NELFA (negative elongation factor complex member A). [provided by Alliance of Genome Resources, Apr 2022]

Nelfa Products(1)

mRNA	Protein	Name
NM_001008339.1	NP_001008340.1	negative elongation factor A

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IMP IMP: Inferred from mutant phenotype	21623364	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of protein modification process	IMP IMP: Inferred from mutant phenotype	21623364	RGD
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	21623364	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

negative elongation factor A

Wolf-Hirschhorn syndrome candidate 2 protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09201	NELFA Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21664	Nelfa Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS28182	Nelfa Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nelfa	NCBI	NCBI:7469

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