2. Gene
  3. Map3k3 - mitogen activated protein kinase kinase kinase 3 Gene

Map3k3 - mitogen activated protein kinase kinase kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 303604 | Gene type: protein coding

About Map3k3

Summary

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including negative regulation of cellular senescence; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of cell migration involved in sprouting angiogenesis. Predicted to act upstream of or within several processes, including blood vessel development; positive regulation of p38MAPK cascade; and protein autophosphorylation. Predicted to be active in cytoplasm. Orthologous to human MAP3K3 (mitogen-activated protein kinase kinase kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Map3k3 Products(1)

mRNA Protein Name
NM_001107058.3 NP_001100528.1 mitogen-activated protein kinase kinase kinase 3
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08056 MAP3K3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18870 Map3k3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25361 Map3k3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map3k3 NCBI NCBI:4215