2. Gene
  3. Sumo1 - small ubiquitin-like modifier 1 Gene

Sumo1 - small ubiquitin-like modifier 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 301442 | Gene type: protein coding

About Sumo1

Summary

Predicted to enable enzyme binding activity; Potassium Channel regulator activity; and protein tag. Predicted to be involved in several processes, including negative regulation of protein import into nucleus; protein stabilization; and regulation of ion transmembrane transporter activity. Predicted to act upstream of or within PML body organization; protein localization to nuclear pore; and regulation of transcription, DNA-templated. Located in several cellular components, including XY body; dendrite; and fibrillar center. Colocalizes with PML body and heterochromatin. Human ortholog(s) of this gene implicated in orofacial cleft 10. Orthologous to human SUMO1 (small ubiquitin like modifier 1). [provided by Alliance of Genome Resources, Apr 2022]

Sumo1 Products(1)

mRNA Protein Name
NM_001009672.1 NP_001009672.1 small ubiquitin-related modifier 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17486098 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
17289031 RGD
Cellular Component GO Annotation Evidence Reference Source
located in PML body IDA
IDA: Inferred from direct assay
15349788 RGD
located in XY body IDA
IDA: Inferred from direct assay
15349788 RGD
located in dendrite IDA
IDA: Inferred from direct assay
17486098 RGD
located in fibrillar center IDA
IDA: Inferred from direct assay
17587596 RGD
located in heterochromatin IDA
IDA: Inferred from direct assay
15349788 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

small ubiquitin-related modifier 1

SMT3 suppressor of mif two 3 homolog 1

SUMO-1

ubiquitin-like 1 (sentrin)

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108702 ML-792 Inhibitor 99.76% Unkown
HY-139662 HB007 Inhibitor 99.73% Unkown
HY-RS14025 SUMO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17276 Sumo1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23730 Sumo1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sumo1 NCBI NCBI:7341