2. Gene
  3. Kdm4b - lysine demethylase 4B Gene

Kdm4b - lysine demethylase 4B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 301128 | Gene type: protein coding

About Kdm4b

Summary

Predicted to enable histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within histone H3-K36 demethylation; histone H3-K9 demethylation; and negative regulation of histone H3-K9 trimethylation. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach Cancer. Orthologous to human KDM4B (lysine demethylase 4B). [provided by Alliance of Genome Resources, Apr 2022]

Kdm4b Products(2)

mRNA Protein Name
NM_001044236.3 NP_001037701.2 lysine-specific demethylase 4B isoform 1
NM_001395633.1 NP_001382562.1 lysine-specific demethylase 4B isoform 2
Protein Preferred Names Protein Names

lysine-specific demethylase 4B

lysine (K)-specific demethylase 4B

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-104048 QC6352 Inhibitor 99.13% Unkown
HY-12725 ML324 Inhibitor 98.35% Unkown
HY-101799 NCGC00244536 Inhibitor 99.70% Unkown
HY-110154 NSC636819 98.90% Unkown
HY-RS07214 KDM4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17132 Kdm4b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23577 Kdm4b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kdm4b NCBI NCBI:23030