2. Gene
  3. Uba5 - ubiquitin-like modifier activating enzyme 5 Gene

Uba5 - ubiquitin-like modifier activating enzyme 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ube1dc1

Gene ID: 300968 | Gene type: protein coding

About Uba5

Summary

Predicted to enable UFM1 activating enzyme activity; protein homodimerization activity; and zinc ion binding activity. Predicted to be involved in several processes, including myeloid cell differentiation; protein K69-linked ufmylation; and reticulophagy. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 24 and developmental and epileptic encephalopathy 44. Orthologous to human UBA5 (ubiquitin like modifier activating enzyme 5). [provided by Alliance of Genome Resources, Apr 2022]

Uba5 Products(1)

mRNA Protein Name
NM_001009669.2 NP_001009669.1 ubiquitin-like modifier-activating enzyme 5
Protein Preferred Names Protein Names

ubiquitin-like modifier-activating enzyme 5

UFM1-activating enzyme

ubiquitin-activating enzyme 5

ubiquitin-activating enzyme E1 domain-containing protein 1

ubiquitin-activating enzyme E1-domain containing 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101836 DKM 2-93 Inhibitor 98.76% Unkown
HY-148266 UBA5-IN-1 Inhibitor ≥98.0% Unkown
HY-RS15322 UBA5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18051 Uba5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24525 Uba5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uba5 NCBI NCBI:79876