2. Gene
  3. APH1B - Aph1b aph-1 homolog B, gamma secretase subunit Gene

APH1B - Aph1b aph-1 homolog B, gamma secretase subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as APH-1B'

Gene ID: 300802 | Gene type: protein coding

About APH1B

Summary

Predicted to enable endopeptidase activator activity and protein-macromolecule adaptor activity. Involved in locomotory behavior. Predicted to be located in transport vesicle. Predicted to be part of gamma-secretase complex. Predicted to be active in endoplasmic reticulum. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human APH1B (aph-1 homolog B, gamma-secretase subunit). [provided by Alliance of Genome Resources, Apr 2022]

APH1B Products(1)

mRNA Protein Name
NM_001047090.2 NP_001040555.1 gamma-secretase subunit APH-1B
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in locomotory behavior IMP
IMP: Inferred from mutant phenotype
15721236 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-secretase subunit APH-1B

APH1B gamma secretase subunit

anterior pharynx defective 1 homolog B

anterior pharynx defective 1b homolog

gamma-secretase subunit APH-1B-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-156011 PSEN1-IN-1 Inhibitor / Unkown
HY-156012 PSEN1-IN-2 Inhibitor / Unkown
HY-RS00818 APH1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22392 Aph1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28916 Aph1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens APH1B NCBI NCBI:83464