2. Gene
  3. Nlrc4 - NLR family, CARD domain containing 4 Gene

Nlrc4 - NLR family, CARD domain containing 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ipaf; Card12

Gene ID: 298784 | Gene type: protein coding

About Nlrc4

Summary

Predicted to enable several functions, including ATP binding activity; Caspase binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including positive regulation of proteolysis; regulation of gene expression; and response to bacterium. Predicted to act upstream of or within regulation of apoptotic process and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be located in cytosol. Predicted to be part of IPAF inflammasome complex. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 4. Orthologous to human NLRC4 (NLR family CARD domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Nlrc4 Products(1)

mRNA Protein Name
NM_001309432.1 NP_001296361.1 NLR family CARD domain-containing protein 4
Protein Preferred Names Protein Names

NLR family CARD domain-containing protein 4

caspase recruitment domain family, member 12

ice protease-activating factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-152670 JC2-11 Inhibitor 98.03% Unkown
HY-148258 GDC-2394 Inhibitor 99.54% Unkown
HY-RS09347 NLRC4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-161669 NLRP3-IN-40 Inhibitor / Unkown
HY-170233 NLRP3-IN-75 Inhibitor / Unkown
HY-RS17988 Nlrc4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24459 Nlrc4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nlrc4 NCBI NCBI:58484