2. Gene
  3. Pin1 - peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Gene

Pin1 - peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 298696 | Gene type: protein coding

About Pin1

Summary

Predicted to enable several functions, including GTPase activating protein binding activity; beta-catenin binding activity; and protein phosphorylated amino acid binding activity. Involved in positive regulation of cell growth involved in cardiac muscle cell development; positive regulation of protein modification process; and regulation of neuron apoptotic process. Located in several cellular components, including cytosol; mitochondrion; and neuron projection. Used to study asthma and secondary hyperparathyroidism. Orthologous to human PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1). [provided by Alliance of Genome Resources, Apr 2022]

Pin1 Products(1)

mRNA Protein Name
NM_001106701.2 NP_001100171.1 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18628984 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
21443524 RGD
involved in positive regulation of cell growth involved in cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
23487407 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
16504941 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
19940183 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-139361 Sulfopin Inhibitor 99.82% Unkown
HY-123847 KPT-6566 Inhibitor ≥98.0% Unkown
HY-128034 PPIase-Parvulin inhibitor Inhibitor 99.79% Unkown
HY-171334 (Rac)-P1D-34 Degrader / Unkown
HY-P4359 Suc-AEPF-AMC Inhibitor 98.67% Unkown
HY-153675 BCPA Modulator 98.51% Unkown
HY-128592 TAB29 Inhibitor / Unkown
HY-171334A P1D-34 Degrader / Unkown
HY-143903 ZL-Pin13 Inhibitor / Unkown
HY-168036 PIN1 inhibitor 3 Inhibitor / Unkown
HY-171442 PIN1 ligand-2 Degrader / Unkown
HY-170766 PIN1 inhibitor 4 Inhibitor / Unkown
HY-168872 API32 Inhibitor / Unkown
HY-137122 3-Pyridine toxoflavin Inhibitor / Unkown
HY-168037 PROTAC PIN1 degrader-1 / Unkown
HY-164895 PIN1 degrader-1 Degrader / Unkown
HY-143902 ZL-Pin01 Inhibitor / Unkown
HY-170429 BJP-07-017-3 Inhibitor / Unkown
HY-171442A (R)-PIN1 ligand-2 / Unkown
HY-W843265 PIN1 inhibitor 6 Inhibitor / Unkown
HY-12135 Poloxipan Inhibitor / Unkown
HY-129310 PIN1 inhibitor 5 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pin1 NCBI NCBI:5300