2. Gene
  3. Gba2 - glucosylceramidase beta 2 Gene

Gba2 - glucosylceramidase beta 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 298399 | Gene type: protein coding

About Gba2

Summary

Predicted to enable glucosylceramidase activity; glucosyltransferase activity; and steryl-beta-glucosidase activity. Predicted to be involved in several processes, including glucosylceramide catabolic process; lipid glycosylation; and regulation of protein polymerization. Predicted to be located in cytosol. Predicted to be extrinsic component of Golgi membrane; extrinsic component of endoplasmic reticulum membrane; and integral component of membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 46. Orthologous to human GBA2 (glucosylceramidase beta 2). [provided by Alliance of Genome Resources, Apr 2022]

Gba2 Products(1)

mRNA Protein Name
NM_001013091.2 NP_001013109.2 non-lysosomal glucosylceramidase
Protein Preferred Names Protein Names

non-lysosomal glucosylceramidase

NLGase

beta-glucocerebrosidase 2

beta-glucosidase 2

bile acid beta-glucosidase GBA2

bile acid glucosyl transferase GBA2

cholesterol glucosyltransferase GBA2

cholesteryl-beta-glucosidase GBA2

glucosidase beta 2

glucosylceramidase 2

non-lysosomal c

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-129411 Sinbaglustat 98.60% Unkown
HY-RS05302 GBA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18361 Gba2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24840 Gba2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gba2 NCBI NCBI:57704