2. Gene
  3. Edem1 - ER degradation enhancing alpha-mannosidase like protein 1 Gene

Edem1 - ER degradation enhancing alpha-mannosidase like protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1563633

Gene ID: 297504 | Gene type: protein coding

About Edem1

Summary

Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Predicted to be involved in positive regulation of retrograde protein transport, ER to cytosol; protein alpha-1,2-demannosylation; and protein targeting to ER. Predicted to act upstream of or within ubiquitin-dependent ERAD pathway. Predicted to be located in aggresome and endoplasmic reticulum quality control compartment. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Edem1 Products(1)

mRNA Protein Name
NM_001305279.1 NP_001292208.1 ER degradation-enhancing alpha-mannosidase-like protein 1
Protein Preferred Names Protein Names

ER degradation-enhancing alpha-mannosidase-like protein 1

ER degradation enhancer, mannosidase alpha-like 1

ER degradation-enhancing alpha-mannosidase-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-131986 LASSBio-1135 Antagonist 99.05% Unkown
HY-RS04157 EDEM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22478 Edem1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29001 Edem1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Edem1 NCBI NCBI:9695