2. Gene
  3. Pla2g2a - phospholipase A2 group IIA Gene

Pla2g2a - phospholipase A2 group IIA Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as sPLA2

Gene ID: 29692 | Gene type: protein coding

About Pla2g2a

Summary

Enables calcium-dependent Phospholipase A2 activity. Involved in phospholipid metabolic process. Located in perinuclear region of cytoplasm and secretory granule. Human ortholog(s) of this gene implicated in cholecystolithiasis; colorectal cancer; gastroesophageal reflux disease; and human immunodeficiency virus infectious disease. Orthologous to human PLA2G2A (Phospholipase A2 group IIA). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g2a Products(1)

mRNA Protein Name
NM_031598.3 NP_113786.3 phospholipase A2, membrane associated precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium-dependent phospholipase A2 activity IDA
IDA: Inferred from direct assay
9487151 RGD
Biological Process GO Annotation Evidence Reference Source
involved in phospholipid metabolic process IDA
IDA: Inferred from direct assay
9487151 RGD
Cellular Component GO Annotation Evidence Reference Source
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
11034413 RGD
located in secretory granule IDA
IDA: Inferred from direct assay
9487151 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipase A2, membrane associated

GIIC sPLA2

eted enzyme type IIA phospholipase A2

group IIA phospholipase A2

phosphatidylcholine 2-acylhydrolase 2A

phospholipase A2, group IIA (platelets, synovial fluid)

platelet phospholipase A2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10621 PLA2G2A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17567 Pla2g2a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24027 Pla2g2a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g2a NCBI NCBI:5320
Mus musculus Pla2g2a NCBI NCBI:18780